When it comes to weight-loss therapy, more isn’t always better. That’s the core message from our latest client survey — and from the findings shared in our new “Lower Dose Data Video.”
Our survey shows that many clients achieve excellent weight-loss outcomes while remaining on significantly lower doses of medication than those used by most online pharmacies. This approach leads to better tolerability, reduced cost, and safer long-term progress.
What Our Survey Shows
From clients using Mounjaro (tirzepatide), the findings were:
- Average weight loss: 17 kg (2.5 stone)
- Average time on treatment: 6 months
- Average dose used: 6.4 mg weekly
- More than half of clients stayed on 5 mg or less
- Dose increases were made only when:
- Weight loss dropped below 0.5–1 kg per week, and
- Clients were tolerating the medication well
These results show that lower doses can be highly effective, particularly when paired with structured dietetic guidance and clinical oversight.
Why Lower Doses Matter
Mounjaro works by mimicking the gut hormones GLP-1 and GIP, reducing appetite and supporting metabolic health. While higher doses can lead to greater absolute weight loss, they also increase the risk of gastrointestinal side effects and are more costly.
A lower-dose approach offers several advantages:
- Fewer side effects
- Lower long-term medication costs
- Better adherence and easier long-term use
- Safer and more sustainable weight loss
- A personalised plan based on individual response
Research Context
Research shows that tirzepatide can deliver exceptional weight-loss results — sometimes up to 20–25% of body weight at higher maintenance doses. However, real-world evidence increasingly demonstrates that many individuals respond well to lower doses, especially when supported by medical and dietetic care.
Key points from current research:
- Higher doses produce the greatest weight loss on average, but tolerability varies.
- Many people lose substantial weight on modest doses, reducing side-effect risk.
- Stopping or reducing medication without support often leads to weight regain.
- GLP-1 medications can cause side effects, and rare serious events have been reported, meaning clinical monitoring is essential.
What This Means for Our Patients
At Weight Loss Medics, we use a data-driven, safety-first approach:
- We prescribe the lowest effective dose.
- We increase the dose only when clinically needed.
- Clients receive support from specialist doctors and registered dietitians.
- The aim is to deliver strong results while minimising risk, cost, and side effects.
This approach allows clients to achieve meaningful, sustainable weight loss with confidence and expert support at every stage.